Microsporidiosis

Microsporidiosis in zebrafish

Waterborne Outbreak of Microsporidiosis

host cellular immune response among HTLV-I carriers. In data published elsewhere, we documented subclinical immunosuppression on the basis of the association of HTLV-I infection with reduced response to the tuberculin-purified protein derivative (PPD) recall antigen [3, 4]. In vitro studies suggest that the nonresponsiveness to PPD in these HTLV-I carriers may be related to a lack of IFN-g prod...

Microsporidiosis in zebrafish research facilities.

Pseudoloma neurophilia (Microsporidia) is the most common pathogen detected in zebrafish (Danio rerio) from research facilities. The parasite infects the central nervous system and muscle and may be associated with emaciation and skeletal deformities. However, many fish exhibit subclinical infections. Another microsporidium, Pleistophora hyphessobryconis, has recently been detected in a few zeb...

Microsporidiosis in Vertebrate Companion Exotic Animals

Veterinarians caring for companion animals may encounter microsporidia in various host species, and diagnosis and treatment of these fungal organisms can be particularly challenging. Fourteen microsporidial species have been reported to infect humans and some of them are zoonotic; however, to date, direct zoonotic transmission is difficult to document versus transit through the digestive tract....

Disseminated Microsporidiosis in an Immunosuppressed Patient

We report a case of disseminated microsporidiosis in a patient with multiple myeloma who had received an allogeneic stem cell transplant requiring substantial immunosuppression. The causative organism was identified as Tubulinosema acridophagus, confirming this genus of microsporidia as a novel human pathogen.